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A key component to wellness is gut health. But what determines if you have a healthy gut?  On this week’s episode of Well, Now, we dive into the fascinating world of the gut microbiome, a collection of bacteria and sometimes fungi that live in the human digestive system.  We are provided with insight from Dr. Colin Hill, professor of Microbiology at APC Microbiome Ireland on how to properly take care of your microbiome and why it is essential If you liked this episode, check out – Doctors Agree: Obesity is a Disease. The Public Needs to Catch Up. Well, Now is hosted by Dr. Kavita Patel and registered dietitian nutritionist Maya Feller. Editing and podcast production by Kristie Taiwo-Makanjuola and Vic Whitley-Berry. Editorial oversight by Alicia Montgomery. Send your comments and recommendations on what to cover to wellnow@slate.com. Want to listen to Well, Now uninterrupted? Subscribe to Slate Plus to immediately unlock ad-free listening to Well, Now and all your other favorite Slate podcasts.  Subscribe now

From a young age, James T. Morrison used drugs to help him feel better. He started with pills that were prescribed to him–medications like Xanax and Klonopin–but he soon moved on to basically whatever he could get his hands on. In this episode, James discusses his experience with substance use disorder, housing instability, and the criminal justice system. At a time when public officials and policy experts are debating ways to address the overdose crisis in the U.S., James discusses what humane drug policies could look like and how we as a society need to completely change the way we talk about drug use. We first learned about James’ story from an essay he wrote in Slate titled One More Day. If you’d like to check out some of our previous episodes about substance use and recover, here’s a short list:  I Can't Fix It: A First Responder on Heroin I Felt Like the Story Had To Change: Life After Heroin How Jeff Daniels Got Sober, Again Falling In Love...With Heroin Margo Price After Cheating and Drinking N

Todd is looking for love, but he’s unsure about disclosing something in dating profiles: his multiple sclerosis. With symptoms that are increasingly visible, Todd feels compelled to be upfront about his disability with potential dates—but he doesn’t know when or how to discuss it. On this episode of How To!, Carvell Wallace brings on Jessica Slice and Caroline Cupp, authors of Dateable: Swiping Right, Hooking Up, and Settling Down While Chronically Ill and Disabled. They give Todd guidance on having that talk, navigating ableism, and managing his own internal expectations.   If you liked this episode check out: How To Flirt With Confidence Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have you on the show. Subscribe for free on Apple, Spotify or wherever you listen. How To’s executive producer is Derek John. Joel Meyer is our senior editor/producer. The show is produced by Rosemary Belson, with Kevin Bendis and Sara McCrae.

We all know about the mental health crisis wreaking havoc throughout the nation and world.  On this week’s episode of Well, Now we’re continuing our ongoing discussions of mental health, and this time we’re tackling men’s mental health as a whole.  Prime’s new show Counsel Culture, hosted by Nick Cannon and medical professionals across the spectrum, invites men to open up about their histories with anxiety, depression, grief, addiction, and more. Dr. Mike Dow is the resident psychotherapist for the program. If you liked this episode, check out: Eating Disorders Are Rising Among Boys. Why? Well, Now is hosted by registered dietitian nutritionist Maya Feller and Dr. Kavita Patel. Podcast production by Vic Whitley-Berry with editorial oversight by Alicia Montgomery. Send your comments and recommendations on what to cover to wellnow@slate.com  Want to listen to Well, Now uninterrupted? Subscribe to Slate Plus to immediately unlock ad-free listening to Well, Now and all your other favorite Slate podcasts.  Subscri

“Home diagnostics” are a $5 billion industry—and growing. Spurred by social media, people are buying into at-home health tests, without input from their doctors, and often, not even the FDA.   Guest:  Elizabeth Dwoskin, reporter for the Washington Post Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Air-conditioning can feel like the only way to get through increasingly hot summers, but it’s an expensive, power-hungry way to keep cool.  How necessary is it? And how necessary is it to raise our thermostats up from 72 degrees? Guest: Adam Clark Estes, senior technology correspondent at Vox. Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Jules talks to Gender Doula Eli Lawliet. They break down what it means to offer non-medical support to people during transition, the long history of trans support networks, and the value of ritual and spirituality during transition. Learn more about your ad choices. Visit megaphone.fm/adchoices

Few drugs in the last century have changed the landscape of healthcare and weight management like GLP-1 agonist drugs — drugs like Ozempic and WeGovy. On this week’s episode of Well, Now we talk with Harvard professor and clinician Dr. Fatima Cody Stanford.  Her research revolutionized obesity medicine and helped pave the way to get a diabetes drug approved for treating a condition millions have in the U.S. If you liked this episode, check out – Doctors Agree: Obesity is a Disease. The Public Needs to Catch Up. Well, Now is hosted by Dr. Kavita Patel and registered dietitian nutritionist Maya Feller. Editing and podcast production by Vic Whitley-Berry.  Production assistance from Kristie Taiwo-Makanjuola.  Editorial oversight by Alicia Montgomery. Send your comments and recommendations on what to cover to wellnow@slate.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Last week the Supreme Court ruled a $6 billion settlement between Purdue Pharma and victims of the opioid crisis could not move forward, because it granted immunity to the Sackler family, the principal owners of Purdue. For one of the litigants, a mother who has lost two sons to overdoses, the decision felt like “a sucker punch.” Guest: Cheryl Juaire, part of the bankruptcy settlement with Purdue Pharma and founder of the non-profit organization Team Sharing, a support group for parents who have lost kids to overdoses. Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Learn more about your ad choices. Visit megaphone.fm/adchoices

Women, girls, and people assigned female at birth make up more than half of the world’s population. Yet, many of them say they don’t feel supported, heard, or cared for in the doctor’s office — even in spaces designed specifically for their care like obstetrics and gynecology. Dr. Sharon Malone, veteran OB/GYN, is on a mission to change that. On this week’s episode of Well, Now, we speak with Dr. Malone on how to advocate for the care you deserve at every stage of life. It’s the subject of her new book Grown Woman Talk: Your Guide to Getting and Staying Healthy. If you liked this episode, check out: How Doulas Make Childbirth Safer for Everyone Well, Now is hosted by Dr. Kavita Patel and registered dietitian nutritionist Maya Feller. Editing and podcast production by Vic Whitley-Berry with editorial oversight by Alicia Montgomery. Production assistance from Kristie Taiwo-Makanjuola. Send your comments and recommendations on what to cover to wellnow@slate.com Learn more about your ad choices. Visit megaphone.f

When Roe v. Wade was overturned, a near-total abortion ban was triggered in Idaho, allowing for health exceptions only when “necessary to prevent the death of the pregnant woman.” But a case that found the ban in conflict with a federal law known as “EMTALA” went all the way to the Supreme Court, before being sent back to lower courts—neither overturning nor upholding Idaho’s ban.  Guest: Dr. Stacy Seyb, a maternal-fetal medicine specialist in Boise, Idaho.  Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Learn more about your ad choices. Visit megaphone.fm/adchoices

The story of IUDs is a story of technology, reproductive rights, shortcomings in communication about women’s health, and politics.  Guest: Mia Armstrong-Lopez, managing editor at ASU Media Enterprise and author of a recent piece on IUDs for Slate.  Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Saying any one storm or heat wave or weather in general was “caused by climate change” is tricky—summer is, after all, usually pretty hot, and storms happen. But researchers are working on a model that brings “climate change” from abstract into the particular.   Guest: Daniel Swain, climate scientist at the UCLA Institute of the Environment and Sustainability, studying how extreme events are changing on a warming Earth. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

For years, psychiatrists have been researching new methods to help people with treatment-resistant mental illness. These include severe cases of depression, post-traumatic stress disorder, and other debilitating diagnoses. One type of drug has seen some positive results in clinical trials: psychedelics like psilocybin, MDMA, ketamine, and LSD. In professional medical settings, they’re used as a part of a multifaceted approach to mental health treatment, including supervised therapy sessions while a patient is on a drug. Recently the pharmaceutical manufacturer Lykos petitioned the FDA to approve the psychedelic MDMA as a part of caring for treatment-resistant PTSD. Earlier this month, an advisory committee to the FDA released their vote of rejecting to approve the drug.  Now it’s up to the FDA to make the final call, but the odds are not in the favor of Lykos and many psychiatrists and patients who’ve seen positive outcomes as a result of these MDMA-assisted trials. Psychiatrist and entrepreneur Dave Rabin is

The Supreme Court’s unanimous decision to uphold access to mifepristone left the door open for another case to be brought to ban the abortion pill. This physician is eager for another chance.  Guest: Dr. Christina Francis, CEO of the American Association of Pro-Life Obstetricians and Gynecologists (AAPLOG), associate scholar with the Charlotte Lozier Institute, a board member of Indiana Right to Life, physician member of the Abortion Pill Reversal Network.  Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today, we’re revisiting one of our favorite episodes from September 2023 with Dr. Orna Guralnik (host of Showtime’s Couples Therapy). In this episode, Dr. Orna Guralnik joins Prudie (Jenée Desmond-Harris) to answer letters from readers about what to do when a friend is obsessed with misogynistic love and relationship podcasts, when your husband just can’t figure out birthday gifts, and when you’re wondering “Does therapy just not work for me?” If you want more Dear Prudence, join Slate Plus, Slate’s membership program. Jenée answers an extra question every week, just for members. Go to Slate.com/prudieplus to sign up. It’s just $15 for your first three months. Podcast production by Se’era Spragley Ricks and Daisy Rosario, with help from Maura Currie. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Supreme Court is soon expected to decide Grants Pass v. Johnson, a case where a town’s efforts to remove unhoused people from its parks became “cruel and unusual,” according to lower courts. Guest: Dr. Bruce Murray, chief medical officer for the Mobile Integrative Navigation Team (MINT) in Josephine County, Oregon. Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Learn more about your ad choices. Visit megaphone.fm/adchoices

Everyone knows the quality of the air we breathe directly affects our health.  As the summer rolls along and more people seek reprieve from the heat indoors, it’s important to be sure our indoor air is clean and toxin-free. One pollutant to keep an eye out for is mold. Mold inside a home could hurt your health both immediately and in the long term. So to help us better understand how to spot mold in the home and how to get rid of it, we’re joined by air quality expert Michael Rubino, president of the Change the Air Foundation and the founder of HomeCleanse. If you liked this episode, check out – Doctors Agree: Obesity is a Disease. The Public Needs to Catch Up. Well, Now is hosted by registered dietitian nutritionist Maya Feller and Dr. Kavita Patel. Editing and podcast production by Vic Whitley-Berry, with support this week from Kristie Taiwo-Makanjuola.  Editorial oversight from Alicia Montgomery, Vice President of Slate Audio. Send your comments and recommendations on what to cover to wellnow@slate.com Lea

Meg once was a terror in the world of roller derby. But these days, her sedentary lifestyle is making everyday physical activities a tad daunting. (We’re looking at you, groceries that need to be carried up four flights of stairs!). She wants to start lifting weights, but she’s unsure where to start—and whether she can avoid the bro-culture of many weight rooms. On this episode of How To!: Courtney Martin brings in writer and powerlifter Mikala Jamison, who was in Meg’s shoes not that long ago. She shares how she got started, why lifting is a lifelong journey, and what we can learn from the current zeitgeist for women’s strength training. Resources mentioned:  Mikala’s Substack, Body Type  Book with simple lifting guide Fitness trainer Meg Gallagher on Instagram If you liked this episode check out: How To Be Free Of Body Shame or How To Stick to Your New Year’s Resolutions Do you have a problem that needs solving? Send us a note at howto@slate.com or leave us a voicemail at 646-495-4001 and we might have y

Mark Duplass’s first big dream came true when he was 28: a movie he wrote and directed with his brother, Jay, got into The Sundance Film Festival. It was a major accomplishment, but Mark was miserable. “The week after Sundance was probably one of the worst weeks of my life because I realized I hit the top of the mountain. The top of the mountain didn't make me happy. So now what am I going to do?” In this episode, filmmaker Mark Duplass talks about managing depression, what it’s like to have a creative partnership with his brother, and how they talk about making and spending money. “If I didn't have Jay as a partner, I would make a hundred mediocre movies a year, and if he didn't have me, he would die with two thirds of the greatest film ever made, not finished.” Read: With Hollywood shedding jobs, here is help for coping with the slowdown Podcast production by Andrew Dunn Death, Sex & Money is now produced by Slate! To support us and our colleagues, please sign up for our membership program, Slate Plus! Memb