New Books In Science

Ann Blair and Kaspar von Greyerz have edited an outstanding volume that breaks important new ground in the history of early modern science and religion. As the contributors to this volume demonstrate, the long-standing discussion of natural theology gave way in the mid-seventeenth century to a new conversation about physico-theology, a distinctive genre of science and religion writing that emphasised the goodness and the predictability of the divine being. Emerging first in the immediate aftermath of the crisis of the English civil wars, this discourse emphasised order and causality, and subjected the being of God to the science of order that was emerging in the same period. But, constructed to explain the benevolence of the creator and creation, physico-theology struggled to make sense of creaturely suffering, and eventually was understood as undermining its own presuppositions. Just published by Johns Hopkins University Press, Physico-Theology: Religion and Science in Europe, 1650-1750 will be a landmark te

In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. Alisha R

Normally we write blogposts that try to convince you to listen to a conversation with an author about their fascinating book. In the time of COVID-19, it doesn't seem necessary to have to sell you on why you should listen to this podcast. Suffice it to say that Mitchell Hammond’s excellent survey of a dozen deadly diseases is a must-read primer to make sense of epidemic history. In Epidemics and the Modern World (University of Toronto Press, 2020), he balances the science of disease etiology and disease cycles with political, socio-economic, and cultural contexts. Read this book! Mitchell L. Hammond, an Assistant Professor at the University of Victoria in beautiful British Columbia. Dr. Hammond studied at Yale, where he earned a BA in Political Science and a MA in Religious History before getting another MA and a PhD in European History at the University of Virginia. His dissertation was entitled “The Origins of Civic Health Care in Early Modern Germany”. He has published several articles and book chapters on

Listen to this interview of David Payne, who is Chief Careers Editor at Nature. We talk about high quality writing, about the gracious community of scientists, and about diversity, diversity, diversity. Interviewer : "What is the one thing you hope, for sure, that every piece of Careers content will achieve?" David Payne : "Oh, that's a question, isn't it? You know what, I think it is about emotion. And I just want it to––not tug at your heartstrings, that sounds cheesy––but I feel, we spend so much time at work, and work does define us, rightly or wrongly, actually. So much of what we do is mediated through the jobs that we do. We spend so much time with our colleagues, and probably more than we do with family members often. So, I just hope that every piece we publish resonates. We can't resonate with everybody, of course, because it's a very diverse workforce in science. But, whenever I read any piece of content, I always think, how many boxes are we ticking here. You know, who is going to be interested in

Blending history, science, and culture, a stunning and highly engaging evolutionary story exploring how walking on two legs allowed humans to become the planet’s dominant species. Humans are the only mammals to walk on two, rather than four legs—a locomotion known as bipedalism. We strive to be upstanding citizens, honor those who stand tall and proud, and take a stand against injustices. We follow in each other’s footsteps and celebrate a child’s beginning to walk. But why, and how, exactly, did we take our first steps? And at what cost? Bipedalism has its drawbacks: giving birth is more difficult and dangerous; our running speed is much slower than other animals; and we suffer a variety of ailments, from hernias to sinus problems. In First Steps: How Upright Walking Made Us Human (Harper, 2021), paleoanthropologist Jeremy DeSilva explores how unusual and extraordinary this seemingly ordinary ability is. A seven-million-year journey to the very origins of the human lineage, First Steps shows how upright walk

Of all forms of alternative medicine, chiropractic is the one that is most generally accepted. In the UK, for instance, chiropractors are regulated by statute and even have their own ‘Royal College of Chiropractic’. In the US, chiropractic’s country of origin, most chiropractors carry the title ‘doctor’ and many consumers believe they are medically trained. Despite this high level of acceptance, chiropractic is wide open to criticism. The claims and assumptions made by chiropractors are far from evidence based. Chiropractic manipulations are of doubtful effectiveness and have regularly been associated with severe adverse effects, including multiple fatalities. The advice issued by chiropractors to patients and consumers is often less than responsible. The behaviour of chiropractors and their organisations is frequently less than professional. Edzard Ernst's Chiropractic:' Not All That It's Cracked Up to Be (Springer, 2020) presents and discusses recent evidence in and around chiropractic in a factual and unem

Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief: The Story of Alzheimer's (Columbia UP, 2021) is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles w

An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine: Exposing the Crisis of Credibility in Clinical Research (Wakefield Press, 2020) provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical ind

Would your dog eat you if you died? What are face mites? Why do clowns creep us out? In this illuminating collection of grisly true science stories, journalist Erika Engelhaupt, the writer of National Geographic’s highly acclaimed Gory Details blog, shares the answers to these questions and many more. Gory Details: Adventures from the Dark Side of Science (National Geographic, 2020) explores the strange and shocking realities of our minds, our bodies and our universe, taking readers on a fascinating tour through overlooked but astonishing aspects of biology, anatomy, nature and more, as well as the ways that science helps to break down taboos surrounding such conversation topics as women’s bodies. Blending humor and real science, Engelhaupt shares captivating stories and intriguing research that will alter the way readers view the world. From a peek inside the world's smallest crime scenes to a hands-on look at maggot farming, Gory Details features top-notch reporting, interviews with leading scientists and a

Viruses are not very different from machines that process information, and thus, how the virus functions can be simulated on a computer. This ability to “imitate” the way viruses behave is particularly useful today, as we battle the impact of the coronavirus pandemic and struggle to prepare for similar events. Dr. Klaus Mainzer, Co-founder and Senior Professor at the Carl Friedrich von Weizsäcker Center of the University of Tübingen and President of European Academy of Sciences and Arts in Salzburg, explains this further in a new podcast episode, in which he talks about his book Leben als Maschine: Wie entschlüsseln wir den Corona-Kode? published by Brill. He explains how bringing together the fields of bioinformatics, machine learning, AI, and big data can help us to decipher the workings of the novel coronavirus and, perhaps, be better equipped to deal with such crises in the future. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbook

Based on a viral article, the gripping medical mystery story of Ron Davis, a world-class Stanford geneticist who has put his career on the line to find the cure for chronic fatigue syndrome, the disease killing his son. For the past six years, Whitney Dafoe has been confined to a bedroom in the back of his parents' home, unable to walk, to eat, to speak. The sound of music causes him pain. At one point, the formerly healthy, young, freelance photographer, faced starvation as his 6'3" frame withered to 115 pounds. In desperation, Whitney and his parents went from one specialist to another, and still no answers. Then, finally, a diagnosis: the mysterious disease myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS). Whitney's story is heartbreaking, but it's also one of redemption. It reaches far beyond just one family's harrowing tale.  Today, ME/CFS affects between 1 and 2.5 million Americans--and 20 million people around the world. Those afflicted largely suffer in silence because the disease is lit

One of the questions I am often asked is exactly what do mathematicians do. The short answer is that they look at different mathematical structures, try to deduce their properties, and think about how they might apply to the real world. Math Without Numbers (Dutton, 2020) does a wonderful job of explaining what mathematical structures are, and does so in a fashion that even readers who are uncomfortable with the process of doing mathematics can appreciate and enjoy. There are courses in music and art appreciation, and if there ever are courses in math appreciation, this book would certainly be at or near the top of the reading list. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Can your zip code predict when you will die? Should you space out childhood vaccines? Does talcum powder cause cancer? Why do some doctors recommend e-cigarettes while other doctors recommend you stay away from them? Health information―and misinformation―is all around us, and it can be hard to separate the two. A long history of unethical medical experiments and medical mistakes, along with a host of celebrities spewing anti-science beliefs, has left many wary of science and the scientists who say they should be trusted. How can we unravel the knots of fact and fiction to find out what we should really be concerned about, and what we can laugh off? In Viral BS: Medical Myths and Why We Fall for Them (Johns Hopkins UP, 2021), medical journalist, doctor, professor, and former CDC disease detective Seema Yasmin, driven by a need to set the record straight, dissects some of the most widely circulating medical myths and pseudoscience. Exploring how epidemics of misinformation and disinformation can spread faster t

Imagination with a Straight Jacket Alan Lightman is a writer, physicist, and social entrepreneur. He has served on the faculties of Harvard and the Massachusetts Institute of Technology (MIT) and was the first person at MIT to receive dual faculty appointments in science and in the humanities. He is the author of many books, both fiction and nonfiction, including the international best seller Einstein’s Dreams and The Diagnosis, a finalist for the National Book Award. This episode goes to both what’s epic in scope and to what’s more intimate and personal. Epic is knowledge now about how the universe began and that it will end with the sun basically engulfing the earth and then burning out. More personal is that the book explores the moral, even religious issues that scientific knowledge brings with it. Most of all, this episode explores the act of intellectual inquiry and exploration through the careers of leading scientists. Dan Hill, PhD, is the author of eight books and leads Sensory Logic, Inc. (https://w

The fallacy sold to many of us is that the penis signals dominance and power. But this wry and penetrating book reveals that in fact nature did not shape the penis–or the human attached to it–to have the upper…hand. Phallacy looks closely at some of nature’s more remarkable examples of penises and the many lessons to learn from them. In tracing how we ended up positioning our nondescript penis as a pulsing, awe-inspiring shaft of all masculinity and human dominance, Phallacy also shows what can we do to put that penis back where it belongs. Emphasizing our human capacities for impulse control, Phallacy ultimately challenges the toxic message that the penis makes the man and the man can’t control himself. With instructive illustrations of unusual genitalia and tales of animal mating rituals that will make you particularly happy you are not a bedbug, Phallacy shows where humans fit on the continuum from fun to fatal phalli and why the human penis is an implement for intimacy, not intimidation. Emily Anthes is a

On Task: How Our Brain Gets Things Done (Princeton UP, 2020) is a look at the extraordinary ways the brain turns thoughts into actions—and how this shapes our everyday lives.  Why is it hard to text and drive at the same time? How do you resist eating that extra piece of cake? Why does staring at a tax form feel mentally exhausting? Why can your child expertly fix the computer and yet still forget to put on a coat? From making a cup of coffee to buying a house to changing the world around them, humans are uniquely able to execute necessary actions. How do we do it? Or in other words, how do our brains get things done?  In On Task, cognitive neuroscientist David Badre presents the first authoritative introduction to the neuroscience of cognitive control—the remarkable ways that our brains devise sophisticated actions to achieve our goals. We barely notice this routine part of our lives. Yet, cognitive control, also known as executive function, is an astonishing phenomenon that has a profound impact on our well

Few astronomers in the 20th century did as much to expand our understanding of the universe as Vera Rubin. To tell her remarkable story in their biography Vera Rubin: A Life (Belknap Press, 2021), authors Jacqueline and Simon Mitton describe both the range of her accomplishments as well as the barriers she overcame in order to achieve them.  As they explain, Rubin was drawn early to the study of the stars, determining early in her life that she wanted to be an astronomer. To become one she had to overcome the assumptions of many of her peers that science was not an appropriate field of study for a woman, or that she would abandon her studies once she married and had children.  Defying their expectations, Rubin balanced child-rearing with earning her doctorate in astronomy and undertaking observational work. Though she participated in a number of different studies, her passion was for understanding galaxies, and her discoveries proved critical for the acceptance of the existence of dark matter in the universe.

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also c

Vaccines make us wholly or partly immune to disease, such as Covid-19. But what is it to be immune? What is an immune system, and what does it do? In its beginnings, immunology was considered the science of the self/non-self distinction: the immune system comprised the self’s defenses against invading non-self pathogens, and was a sophisticated system possessed only by vertebrates. In Philosophy of Immunology (Cambridge University Press, 2020), Thomas Pradeu explains why these traditional conceptions have been upended over the past 20 years or so. It is now accepted that even single celled organisms have immune systems and that immune systems are also active in many biological activities, including regulation of foreign entities that are not part of the body but are not pathogens either, such as the gut microbiome. Pradeu, who is senior researcher at CNRS and University of Bordeau, defends his view of the individual as an immunologically unified chimera, and speculates about the implications for our understan

A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer’s disease, and Parkinson’s disease. Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In his book The Future of Brain Repair: A Realist's Guide to Stem Cell Therapy (MIT Press, 2020), neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer’s disease, Parkinson’s disease, and spinal cord injuries. Certainly brain disorders are in need of effective treatments. These disorders don’t just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because