Acs Research - Theorylab

Lung squamous cell carcinoma (LSCC) is the 2nd most common sub-type of lung cancer, accounting for around 30% of lung cancer diagnoses. And it is a particularly deadly disease that’s characterized by poor therapeutic response, a high relapse rate, and poor prognosis. Furthermore, unlike other subtypes of lung cancer, to date there are no therapies to specifically target the LSCC subtype. Verline Justilien, PhD, has an American Cancer Society grant to study an oncogenic protein called Ect2. Too much of it is a bad thing, and the more you have of it as a LSCC patient, the worse your prognosis is. What if we could know which patients have a worse prognosis, so we could treat them more aggressively? What if a therapy could target Ect2? Dr. Justilien takes us through her very promising research into a kind of cancer where we urgently need progress. And she also Verline Justilien, PhD, is Assistant Professor of Cancer Biology at the Mayo Clinic. 3:28 – What is lung squamous cell carcinoma (LSCC)? 5:33 – A