Acs Research - Theorylab

Lung cancer is the leading cause of cancer death among both men and women in the United States and worldwide. Small cell lung cancer comprises 15-17% of lung cancer cases, and it is the most aggressive subtype of lung cancer, growing rapidly and spreading to other organs quickly. Luke Hoeppner, PhD, received American Cancer Society funding to test whether therapeutically targeting a specific molecular pathway inhibits small cell lung cancer growth. Dr. Hoeppner’s lab was the first to report that activation of this particular pathway, called dopamine signaling, inhibits other forms of lung cancer growth. By therapeutically altering the dopamine signaling pathway, he hopes to inhibit small cell lung cancer progression and drug resistance, facilitating further advancement to new treatments. For more information about lung cancer, visit https://www.cancer.org/cancer/lung-cancer.html. Luke Hoeppner, PhD, is Assistant Professor and leader of the Cancer Biology research section at The Hormel Institute, Univer