Pure Dog Talk

211 – Dwarfism: When the Right Gene Goes Wrong…. | Pure Dog Talk

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Sinopsis

The Dark Side of the Dwarf Gene Dr. Theresa Nesbitt talked last week about the purpose-bred dogs that evolved with short legs to do very specific jobs. Today she talks about “the dark side of the dwarf gene” and what happens when things go wrong when you’re trying to do it right. Dwarf genes have been around for more than 4000 years, Nesbitt said. They are solidly entrenched in some breeds that are specifically “fit for function” for the job they were meant to do. “Everything that isn’t normal, isn’t pathological,” Nesbitt said. Too much of a good thing Sometimes, though, breeders can get “too much of a good thing,” Nesbitt added. She also shared tremendous information on the various genetic disorders of dogs who aren’t supposed to be dwarfs. Nesbitt provided layman’s translation for a lot of medical terminology. She helped decipher topics like retro genes, epigenetics, genes that inadvertently land on the wrong chromosome and more. Making words like achondroplasia make sense to those of us without a medi