Long Now: Seminars About Long-term Thinking

Beth Shapiro is far from a giddy enthusiast about de-extinction. She knows more than nearly anyone about the subject because she is a highly regarded biologist in the middle of the two leading efforts in the new field—to resurrect extinct woolly mammoths and passenger pigeons. She knows exactly how challenging the whole process will be and how imperfect the later stages of success might appear. An evolutionary biologist who created and runs the paleogenomics lab at UC Santa Cruz, Shapiro is a careful skeptic, a great story teller and explainer, and an extremely productive scientist. In this talk she spans the full de-extinction narrative from DNA editing all the way to revived populations in the wild—from lab work with CRISPR Cas 9 and primordial germ cells through to the ethical and practical issues of restoring a long-absent keystone species in its former ecosystem. “The goal of de-extinction,” she points out, “is to restore ecosystems; to reinstate interactions between species that no longer exist b