Diabetes Core Update

This issue will review: Real-World Prospective Validation and Economic Evaluation of Deep Learning-Based Diabetic Retinopathy Detection from Fundus Photographs: A Systematic Review and Meta-Analysis. Diabetes Care 2026;49:510–525; An oral small-molecule GLP-1 receptor agonist for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial. The Lancet 2025;406:2929-2944; FDA removal of SI for GLP-1s – FDA Announcement Neil Read/John Comment; Effectiveness and Safety of Statins in Type 2 Diabetes According to Baseline Cardiovascular Risk: A Target Trial Emulation Study. Ann Intern Med 2025;172:157-167; and GLP-1 Receptor Agonists and Risk of Optic Nerve or Vision-Threatening Events in Patients with Type 2 Diabetes or Cardiometabolic Diseases: A Meta-Analysis of Randomized Controlled Trials. Diabetes Care 2026;49:526-535. Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles