Authentic Biochemistry

Dr Guerra examines proteases and protease inhibitors in ovarian and hepatocellular cancers and their pathobiochemical mechanisms. 03 July 2020.

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Sinopsis

Dr Guerra presents how a protease inhibitor protects a serine protease that is linked to ovarian cancer progression plus how protease inhibitor polymerization overloads the Endoplasmic Reticulum Associated Degradation pathway and Unfolded Protein Response to induce autophagy-linked Hepatocellular Carcinoma. Finally,  a mechanistic step-wise summary of the serine protease catalytic triad  is presented. Published 03 July 2020. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message